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Delayed union of femoral fractures in older rats:decreased gene expression

BACKGROUND: Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26 weeks. The possible role of altered mRNA gene expression in this delayed union was studied. Closed mid-shaft femoral fractures were ind...

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Detalhes bibliográficos
Main Authors: Meyer, Ralph A, Meyer, Martha H, Phieffer, Laura S, Banks, David M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34552/
https://ncbi.nlm.nih.gov/pubmed/11454240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-2-2
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