Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

Plasmids have been constructed that direct the synthesis in Escherichia coli of heavy chains and/or light chains of an anti-carcinoembryonic antigen (CEA) antibody. Another plasmid was constructed for expression of a truncated form of heavy chain (Fd' fragment) in E. coli. Functional CEA-bindin...

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Autors principals: Cabilly, S, Riggs, A D, Pande, H, Shively, J E, Holmes, W E, Rey, M, Perry, L J, Wetzel, R, Heyneker, H L
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC345489/
https://ncbi.nlm.nih.gov/pubmed/6374653
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