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Thymus-derived lymphocytes and their interactions with macrophages are required for the production of osteoclast-activating factor in the mouse.

A bone-resorbing factor, comparable to the osteoclast-activating factor (OAF) produced from peripheral blood leukocytes, is shown to be produced by murine spleen cells activated with the T-cell mitogen Con A. Murine OAF is demonstrated here as being a product of the interaction between thymus-derive...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Horowitz, M, Vignery, A, Gershon, R K, Baron, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6609360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2181
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