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Excess of leptin inhibits hypothalamic KiSS-1 expression in pubertal mice

PURPOSE: Leptin has been considered a link between metabolic state and reproductive activity. Defective reproductive function can occur in leptin-deficient and leptin-excessive conditions. The aim of this study was to examine the effects of centrally injected leptin on the hypothalamic KiSS-1 system...

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Autors principals: Ahn, Sung Yeon, Yang, Sei Won, Lee, Hee Jae, Byun, Jong Seon, Om, Ji Yeon, Shin, Choong Ho
Format: Artigo
Idioma:Inglês
Publicat: The Korean Pediatric Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454576/
https://ncbi.nlm.nih.gov/pubmed/23049591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3345/kjp.2012.55.9.337
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