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Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

The wild-type mouse hypoxanthine phosphoribosyltransferase (HPRT; IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) gene has been isolated from genomic libraries and its structure has been determined. This X chromosome-linked gene is greater than 33 kilobases long and is split into nine exons...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Melton, D W, Konecki, D S, Brennand, J, Caskey, C T
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345454/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6326107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2147
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