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Using Catalytic Atom Maps to Predict the Catalytic Functions Present in Enzyme Active Sites

Catalytic Atom Maps (CAMs) are minimal models of enzyme active sites. The structures in the Protein Data Bank (PDB) were examined to determine if proteins with CAM-like geometries in their active sites all share the same catalytic function. We combined the CAM-based search protocol with a filter bas...

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Detalhes bibliográficos
Main Authors: Nosrati, Geoffrey R., Houk, K. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454523/
https://ncbi.nlm.nih.gov/pubmed/22909276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3008438
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