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Using Catalytic Atom Maps to Predict the Catalytic Functions Present in Enzyme Active Sites

Catalytic Atom Maps (CAMs) are minimal models of enzyme active sites. The structures in the Protein Data Bank (PDB) were examined to determine if proteins with CAM-like geometries in their active sites all share the same catalytic function. We combined the CAM-based search protocol with a filter bas...

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Bibliographic Details
Main Authors: Nosrati, Geoffrey R., Houk, K. N.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454523/
https://ncbi.nlm.nih.gov/pubmed/22909276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3008438
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