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In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element.

An RNA polymerase I control region essential for initiation of pre-rRNA transcription has been identified by mutagenesis in vitro of mouse rDNA (ribosomal RNA genes) and transcription in a cell-free system derived from Ehrlich ascites cells. Substitution of nucleotides between -35 and -14 by foreign...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Skinner, J A, Ohrlein, A, Grummt, I
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345452/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6326106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2137
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