PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

PHF20 is a multidomain protein and subunit of a lysine acetyltransferase complex that acetylates histone H4 and p53 but whose function is unclear. Using biochemical, biophysical and cellular approaches, we determined that PHF20 is a direct regulator of p53. A Tudor domain in PHF20 recognized p53 dim...

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Detalhes bibliográficos
Main Authors: Cui, Gaofeng, Park, Sungman, Badeaux, Aimee I, Kim, Donghwa, Lee, Joseph, Thompson, James R, Yan, Fei, Kaneko, Satoshi, Yuan, Zengqiang, Botuyan, Maria Victoria, Bedford, Mark T, Cheng, Jin Q, Mer, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454513/
https://ncbi.nlm.nih.gov/pubmed/22864287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2353
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