Pharmacogenetic Analysis of Pediatric Patients with Acute Lymphoblastic Leukemia: A Possible Association between Survival Rate and ITPA Polymorphism

Genetic polymorphisms are important factors in the effects and toxicity of chemotherapeutics. To analyze the pharmacogenetic and ethnic differences in chemotherapeutics, major genes implicated in the treatment of acute lymphoblastic leukemia (ALL) were analyzed. Eighteen loci of 16 genes in 100 pati...

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Autors principals: Kim, Hyery, Kang, Hyoung Jin, Kim, Hyo Jeong, Jang, Mi Kyung, Kim, Nam Hee, Oh, Yongtaek, Han, Byoung-Don, Choi, Ji-Yeob, Kim, Chul Woo, Lee, Ji Won, Park, Kyung Duk, Shin, Hee Young, Ahn, Hyo Seop
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454425/
https://ncbi.nlm.nih.gov/pubmed/23029095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045558
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