Pharmacogenetic Analysis of Pediatric Patients with Acute Lymphoblastic Leukemia: A Possible Association between Survival Rate and ITPA Polymorphism

Genetic polymorphisms are important factors in the effects and toxicity of chemotherapeutics. To analyze the pharmacogenetic and ethnic differences in chemotherapeutics, major genes implicated in the treatment of acute lymphoblastic leukemia (ALL) were analyzed. Eighteen loci of 16 genes in 100 pati...

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Detalhes bibliográficos
Main Authors: Kim, Hyery, Kang, Hyoung Jin, Kim, Hyo Jeong, Jang, Mi Kyung, Kim, Nam Hee, Oh, Yongtaek, Han, Byoung-Don, Choi, Ji-Yeob, Kim, Chul Woo, Lee, Ji Won, Park, Kyung Duk, Shin, Hee Young, Ahn, Hyo Seop
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454425/
https://ncbi.nlm.nih.gov/pubmed/23029095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045558
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