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Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork.

At an early purification stage, DNA polymerase alpha holoenzyme from calf thymus can be separated into four different forms by chromatography on DEAE-cellulose. All four enzyme forms (termed A, B, C, and D) are capable of replicating long single-stranded DNA templates, such as parvoviral DNA or prim...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ottiger, H P, Hübscher, U
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6588375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.13.3993
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