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Inhibition of protein synthesis stimulates the transcription of human beta-interferon genes in Chinese hamster ovary cells.

Using Chinese hamster ovary (CHO) cells transfected with a plasmid carrying the human beta-interferon gene, we find that inhibitors of protein synthesis, in the absence of any other inducer, stimulate the production of interferon RNA; this effect is maintained in cells in which the plasmid sequences...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ringold, G M, Dieckmann, B, Vannice, J L, Trahey, M, McCormick, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345348/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6330726/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.13.3964
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