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Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

Low density lipoprotein (LDL) incubated with cultured endothelial cells from rabbit aorta or human umbilical vein is altered in several ways (EC-modified): (i) It is degraded by macrophages much faster than LDL similarly incubated in the absence of cells or incubated with fibroblasts. (ii) Its elect...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Steinbrecher, U P, Parthasarathy, S, Leake, D S, Witztum, J L, Steinberg, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345326/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.12.3883
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