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A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells.

The Epstein-Barr viral (EBV) genome of approximately equal to 170 kilobase pairs (kbp) is maintained as a plasmid in human B lymphoblasts transformed by the virus. We have identified a cis-acting element within 1.8 kbp of the viral genome that allows recombinant plasmids carrying it to be selected a...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Yates, J, Warren, N, Reisman, D, Sugden, B
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1984
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6328526/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.12.3806
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