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Method to map antigenic determinants recognized by monoclonal antibodies: localization of a determinant of virus neutralization on the feline leukemia virus envelope protein gp70.

A method is presented whereby antigenic determinants recognized by specific monoclonal antibodies can be mapped to specific sites on a protein sequence with high resolution. Short DNase I-generated DNA fragments encoding portions of the protein of interest are molecularly cloned into the EcoRI site...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nunberg, J H, Rodgers, G, Gilbert, J H, Snead, R M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6203125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.12.3675
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