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Does sumatriptan cross the blood–brain barrier in animals and man?
Sumatriptan, a relatively hydrophilic triptan, based on several animal studies has been regarded to be unable to cross the blood–brain barrier (BBB). In more recent animal studies there are strong indications that sumatriptan to some extent can cross the BBB. The CNS adverse events of sumatriptan in...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Milan
2009
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3452191/ https://ncbi.nlm.nih.gov/pubmed/20012125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10194-009-0170-y |
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