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Internal homologies in the two aspartokinase-homoserine dehydrogenases of Escherichia coli K-12.

In Escherichia coli, AK I- HDH I and AK II- HDH II are two bifunctional proteins, derived from a common ancestor, that catalyze the first and third reactions of the common pathway leading to threonine and methionine. An extensive amino acid sequence comparison of both molecules reveals two main feat...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ferrara, P, Duchange, N, Zakin, M M, Cohen, G N
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6374650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.10.3019
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