Induction of immunity to a human tumor marker by in vivo administration of anti-idiotypic antibodies in mice.

Anti-idiotypic antibodies are described that were raised against murine monoclonal antibody 8.2, an antibody specific for a human melanoma-associated cell surface marker called p97. The 8.2 idiotopes recognized by this anti-idiotypic antiserum are binding site-associated and are shared by other mono...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Nepom, G T, Nelson, K A, Holbeck, S L, Hellström, I, Hellström, K E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6609369/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.9.2864
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