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Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

To explore the role of DNA methylation in maintaining dosage compensation of X chromosome-linked genes and in regulating the transcriptional activity of "housekeeping" genes, we characterized DNA methylation of active, inactive, and derepressed alleles at the locus for hypoxanthine phosphoribosyltra...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wolf, S F, Jolly, D J, Lunnen, K D, Friedmann, T, Migeon, B R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.9.2806
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