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Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

To explore the role of DNA methylation in maintaining dosage compensation of X chromosome-linked genes and in regulating the transcriptional activity of "housekeeping" genes, we characterized DNA methylation of active, inactive, and derepressed alleles at the locus for hypoxanthine phospho...

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Библиографические подробности
Главные авторы: Wolf, S F, Jolly, D J, Lunnen, K D, Friedmann, T, Migeon, B R
Формат: Artigo
Язык:Inglês
Опубликовано: 1984
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC345159/
https://ncbi.nlm.nih.gov/pubmed/6585829
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