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Development of a human T-cell hybridoma secreting separate B-cell growth and differentiation factors.

A cloned human T-cell hybridoma (7D5) secreting B-cell growth factor (BCGF) and B-cell differentiation factor (BCDF) was established. Supernatant from this hybrid was capable of maintaining proliferation in anti-IgM-activated normal human B cells. In addition, the hybridoma supernatant induced diffe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Butler, J L, Falkoff, R J, Fauci, A S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345084/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6609362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.8.2475
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