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Telomerase as a tumor-associated antigen for cancer immunotherapy
Telomerase reverse transcriptase hTERT is an attractive target for cancer immunotherapy given its broad expression in human tumors and its demonstrated immunogenicity. Human and murine model systems demonstrate that CD8(+) cytotoxic T-lymphocytes (CTL) and CD4(+) helper T-lymphocytes can recognize d...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Kluwer Academic Publishers
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449959/ https://ncbi.nlm.nih.gov/pubmed/19003246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-004-5132-2 |
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