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Telomerase as a tumor-associated antigen for cancer immunotherapy
Telomerase reverse transcriptase hTERT is an attractive target for cancer immunotherapy given its broad expression in human tumors and its demonstrated immunogenicity. Human and murine model systems demonstrate that CD8(+) cytotoxic T-lymphocytes (CTL) and CD4(+) helper T-lymphocytes can recognize d...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Kluwer Academic Publishers
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449959/ https://ncbi.nlm.nih.gov/pubmed/19003246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-004-5132-2 |
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