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Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask

Taguchi’s methods were used for the design of an experimental strategy aimed at optimizing cell density and monoclonal antibody (mAb) production from a spinner flask hybridoma culture. 23G11 is an antibody to the human leukocyte adhesion molecule, CR3 or β 2 integrin (CD11b/CD18). It recognizes spec...

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Detalhes bibliográficos
Main Authors: Kallel, Héla, Zaïri, Hind, Rourou, Samia, Essafi, Makram, Barbouche, Ridha, Dellagi, Koussay, Fathallah, Dahmani M.
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449801/
https://ncbi.nlm.nih.gov/pubmed/19003299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1022437514334
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