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Comparison of RAP-PCR analysis of gene expression in fresh and immortalised rat hepatocyte cell lines
Primary rat hepatocytes dedifferentiate rapidly losing theactivities of the drug metabolising enzymes involved in thedetoxification of xenobiotics in the liver. An alternativeapproach to using primary hepatocytes for toxicity testing isthe development of immortalised hepatocyte cell lines via thetra...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Kluwer Academic Publishers
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449737/ https://ncbi.nlm.nih.gov/pubmed/19003390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008159912634 |
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