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Regulated autocrine growth of CHO cells

The goal of this work was to engineer a CHO cell line capable ofautocrine growth in a fully defined protein-free medium. Thiswas accomplished by stable integration of the genes encodinginsulin-like growth factor I (IGF-I) and transferrin into thegenome of a CHO-K1 cell line. Thelac operator/represso...

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Detalhes bibliográficos
Main Authors: Sunstrom, Noelle-Anne, Sugiyono, Hunt, Sybille, Bailey, Charles, Baig, Masood, Sleigh, Merilyn, Gray, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449732/
https://ncbi.nlm.nih.gov/pubmed/19003379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008194529175
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