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Optimization of monoclonal antibody production: combined effects of potassium acetate and perfusion in a stirred tank bioreactor
To increase the yield of monoclonal antibody in a hybridoma culture, it is important to optimize the combination of several factors including cell density, antibody productivity per cell, and the duration of the culture. Potassium acetate enhances the production of antibodies by cells but sometimes...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Kluwer Academic Publishers
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449610/ https://ncbi.nlm.nih.gov/pubmed/22358596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007914004727 |
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