Interleukin 12 and CD86 Regulate Th1 and Th2 Development Induced by a Range of Antigen Doses Presented by Peyer's Patch and Spleen Cells

In this study, we demonstrate the role of interleukin 12 (IL-12), CD80 and CD86 in T helper type 1 (Th1) and Th2 differentiation induced through antigen presentation by Peyer's patch (PP) and spleen (SPL) cells with various doses of antigen. IL-12 was found to be critical for the induction of T...

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Bibliografiske detaljer
Main Authors: Yoshida, Tadashi, Hachimura, Satoshi, Ishimori, Mina, Ise, Wataru, Totsuka, Mamoru, Ametani, Akio, Kaminogawa, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: Kluwer Academic Publishers 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449607/
https://ncbi.nlm.nih.gov/pubmed/19003211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/B:CYTO.0000039895.11048.1b
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