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In vitro immunization can elicit the expansion of diverse repertoire of B cells from peripheral blood mononuclear cells

We previously developed an in vitro immunization (IVI) protocol of human peripheral blood mononuclear cells (PBMC) for generating antigen-specific human antibodies. In order to clarify whether IVI protocolinduces antigen-specific B cell responses in PBMC, we analyzed family gene usage and sequence o...

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Autores principales: Matsumoto, Shin-ei, Yamashita, Makiko, Katakura, Yoshinori, Noguchi, Eri, Aiba, Yoshihiro, Ichikawa, Akira, Teruya, Kiichiro, Shirahata, Sanetaka
Formato: Artigo
Lenguaje:Inglês
Publicado: Kluwer Academic Publishers 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449408/
https://ncbi.nlm.nih.gov/pubmed/19002881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-9003-x
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