Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors.

Bursal lymphomas induced in chickens by avian leukosis viruses (ALVs) harbor proviral insertions that augment expression of an adjacent cellular oncogene, c-myc. To analyze such insertionally mutagenized c-myc genes in greater detail, we isolated molecular clones from two independent tumors. Precise...

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Bibliographische Detailangaben
Hauptverfasser: Westaway, D, Payne, G, Varmus, H E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC344934/
https://ncbi.nlm.nih.gov/pubmed/6322173
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