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Pumilio 1 Suppresses Multiple Activators of p53 to Safeguard Spermatogenesis
During spermatogenesis, germ cells initially expand exponentially through mitoses. A majority of these cells are then eliminated through p53-mediated apoptosis to maintain germline homeostasis [1–4]. However, the activity of p53 must be precisely modulated, especially suppressed in postmitotic sperm...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449084/ https://ncbi.nlm.nih.gov/pubmed/22342750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.01.039 |
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