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Pumilio 1 Suppresses Multiple Activators of p53 to Safeguard Spermatogenesis

During spermatogenesis, germ cells initially expand exponentially through mitoses. A majority of these cells are then eliminated through p53-mediated apoptosis to maintain germline homeostasis [1–4]. However, the activity of p53 must be precisely modulated, especially suppressed in postmitotic sperm...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, Dong, Zheng, Wei, Lin, Aiping, Uyhazi, Katherine, Zhao, Hongyu, Lin, Haifan
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449084/
https://ncbi.nlm.nih.gov/pubmed/22342750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.01.039
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