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MDM2 Expression Is Repressed by The RNA-Binding Protein RNPC1 via mRNA Stability

The RNA-binding protein RNPC1 is a target of the p53 family and forms a feedback regulatory loop with the p53 family proteins. The MDM2 oncogene, a key negative regulator of p53, plays a critical role in a variety of fundamental cellular processes. MDM2 expression is found to be regulated via gene a...

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Detalhes bibliográficos
Main Authors: Xu, Enshun, Zhang, Jin, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449025/
https://ncbi.nlm.nih.gov/pubmed/22710720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.238
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