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Ixodes scapularis JAK-STAT Pathway Regulates Tick Antimicrobial Peptides, Thereby Controlling the Agent of Human Granulocytic Anaplasmosis

Ixodes scapularis transmits the agent of human granulocytic anaplasmosis, among other pathogens. The mechanisms used by the tick to control Anaplasma phagocytophilum are not known. We demonstrate that the I. scapularis Janus kinase (JAK)–signaling transducer activator of transcription (STAT) pathway...

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Autors principals: Liu, Lei, Dai, Jianfeng, Zhao, Yang O., Narasimhan, Sukanya, Yang, Ying, Zhang, Lili, Fikrig, Erol
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448968/
https://ncbi.nlm.nih.gov/pubmed/22859824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis484
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