Ixodes scapularis JAK-STAT Pathway Regulates Tick Antimicrobial Peptides, Thereby Controlling the Agent of Human Granulocytic Anaplasmosis

Ixodes scapularis transmits the agent of human granulocytic anaplasmosis, among other pathogens. The mechanisms used by the tick to control Anaplasma phagocytophilum are not known. We demonstrate that the I. scapularis Janus kinase (JAK)–signaling transducer activator of transcription (STAT) pathway...

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Detalhes bibliográficos
Main Authors: Liu, Lei, Dai, Jianfeng, Zhao, Yang O., Narasimhan, Sukanya, Yang, Ying, Zhang, Lili, Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448968/
https://ncbi.nlm.nih.gov/pubmed/22859824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis484
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