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Urethral Exudates of Men with Neisseria gonorrhoeae Infections Select a Restricted Lipooligosaccharide Phenotype During Transmission

Neisseria gonorrhoeae lipooligosaccharides (LOSs) induce immunoglobulin G that protects men from experimental infection. This raises the possibility that an LOS vaccine might prevent gonorrhea. Gonococci make different LOS molecules, depending on whether 3 genes, lgtA, lgtC, and lgtD, are in frame (...

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Bibliografiske detaljer
Main Authors: McLaughlin, Stephanie E., Cheng, Hui, Ghanem, Khalil G., Yang, Zhijie, Melendez, Johan, Zenilman, Jonathan, Griffiss, J. McLeod
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448965/
https://ncbi.nlm.nih.gov/pubmed/22904337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis481
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