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1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes

BACKGROUND AND PURPOSE: Pungent constituents of ginger (Zingiber officinale) have beneficial effects on inflammatory pain and arthritic swelling. However, the molecular basis for these pharmacological properties is only partially understood. Here, we investigated the molecular target of 1-dehydro-[1...

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Bibliografiske detaljer
Main Authors: Lee, Hwa Young, Park, Sun Hong, Lee, Misoon, Kim, Hye-Jin, Ryu, Shi Yong, Kim, Nam Doo, Hwang, Bang Yeon, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448918/
https://ncbi.nlm.nih.gov/pubmed/22489648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01980.x
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