1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes

BACKGROUND AND PURPOSE: Pungent constituents of ginger (Zingiber officinale) have beneficial effects on inflammatory pain and arthritic swelling. However, the molecular basis for these pharmacological properties is only partially understood. Here, we investigated the molecular target of 1-dehydro-[1...

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Main Authors: Lee, Hwa Young, Park, Sun Hong, Lee, Misoon, Kim, Hye-Jin, Ryu, Shi Yong, Kim, Nam Doo, Hwang, Bang Yeon, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448918/
https://ncbi.nlm.nih.gov/pubmed/22489648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01980.x
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