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Mitochondrial F(0)F(1)-ATP synthase is a molecular target of 3-iodothyronamine, an endogenous metabolite of thyroid hormone

BACKGROUND AND PURPOSE: 3-iodothyronamine (T1AM) is a metabolite of thyroid hormone acting as a signalling molecule via non-genomic effectors and can reach intracellular targets. Because of the importance of mitochondrial F(0)F(1)-ATP synthase as a drug target, here we evaluated interactions of T1AM...

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Autors principals: Cumero, S, Fogolari, F, Domenis, R, Zucchi, R, Mavelli, I, Contessi, S
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448897/
https://ncbi.nlm.nih.gov/pubmed/22452346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01958.x
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