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Sialidase specificity determined by chemoselective modification of complex sialylated glycans

Sialidases hydrolytically remove sialic acids from sialylated glycoproteins and glycolipids. Sialidases are widely distributed in nature and sialidase-mediated desialylation is implicated in normal and pathological processes. However, mechanisms by which sialidases exert their biological effects rem...

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Detalhes bibliográficos
Main Authors: Parker, Randy B., McCombs, Janet E., Kohler, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448839/
https://ncbi.nlm.nih.gov/pubmed/22704707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300241v
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