Dual lineage-specific expression of Sox17 during mouse embryogenesis

Sox17 is essential for both endoderm development and fetal hematopoietic stem cell (HSC) maintenance. While endoderm-derived organs are well known to originate from Sox17-expressing cells it is less certain whether fetal HSCs also originate from Sox17-expressing cells. By generating a Sox17(GFPCre)...

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Hauptverfasser: Choi, Eunyoung, Kraus, Marine R-C., Lemaire, Laurence A., Yoshimoto, Momoko, Vemula, Sasidhar, Potter, Leah A., Manduchi, Elisabetta, Stoeckert, Christian J., Grapin-Botton, Anne, Magnuson, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448801/
https://ncbi.nlm.nih.gov/pubmed/22865702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1192
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