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Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates

“Trojan horse” antibiotic albomycins are peptidyl nucleosides consisting of a highly modified 4′-thiofuranosyl cytosine moiety and a ferrichrome siderophore that are linked by a peptide bond via a serine residue. While the latter component serves to sequester iron from the environment, the seryl nuc...

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Bibliografski detalji
Glavni autori: Zeng, Yu, Kulkarni, Aditya, Yang, Zhaoyong, Patil, Preeti B., Zhou, Wei, Chi, Xiuling, Lanen, Steven Van, Chen, Shawn
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448783/
https://ncbi.nlm.nih.gov/pubmed/22704654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300173x
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