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A sensitive green fluorescent protein biomarker of N-glycosylation site occupancy

N-glycosylation mediates many biological functions. Genetic defects in the N-glycosylation pathway cause >35 inherited human disorders called congenital disorders of glycosylation (CDGs). As a result, some N-glycosylation sites are unoccupied. Serum transferrin is a diagnostic marker for these pa...

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Hlavní autoři: Losfeld, Marie-Estelle, Soncin, Francesca, Ng, Bobby G., Singec, Ilyas, Freeze, Hudson H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448770/
https://ncbi.nlm.nih.gov/pubmed/22691915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-211656
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