IP-FCM Measures Physiologic Protein-Protein Interactions Modulated by Signal Transduction and Small-Molecule Drug Inhibition

Protein-protein interactions (PPI) mediate the formation of intermolecular networks that control biological signaling. For this reason, PPIs are of outstanding interest in pharmacology, as they display high specificity and may represent a vast pool of potentially druggable targets. However, the stud...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, Stephen E. P., Bida, Anya T., Davis, Tessa R., Sicotte, Hugues, Patterson, Steven E., Gil, Diana, Schrum, Adam G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448684/
https://ncbi.nlm.nih.gov/pubmed/23029201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045722
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