Intravenous apoptotic spleen cell infusion induces a TGF-beta-dependent regulatory T-cell expansion

Apoptotic leukocytes are endowed with immunomodulatory properties that can be used to enhance hematopoietic engraftment and prevent graft-versus-host disease. This apoptotic cell-induced tolerogenic effect is mediated by host macrophages and not recipient dendritic cells or donor phagocytes present...

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Detalhes bibliográficos
Main Authors: Kleinclauss, François M., Perruche, Sylvain, Masson, Emeline, De Carvalho Bittencourt, Marcelo, Biichle, Sabeha, Remy-Martin, Jean-Paul, Ferrand, Christophe, Martin, Mael, Bittard, Hugues, Chalopin, Jean-Marc, Seilles, Estelle, Tiberghien, Pierre, Saas, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448559/
https://ncbi.nlm.nih.gov/pubmed/15962005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4401699
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