Tol2 Gene Trap Integrations in the Zebrafish Amyloid Precursor Protein Genes appa and aplp2 Reveal Accumulation of Secreted APP at the Embryonic Veins

BACKGROUND: The single spanning transmembrane amyloid precursor protein (APP) and its proteolytic product, amyloid-beta (Aβ) peptide, have been intensely studied due to their role in the pathogenesis of Alzheimer’s disease. However, the biological role of the secreted ectodomain of APP, which is als...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: LIAO, HSIN-KAI, WANG, YING, NOACK WATT, KRISTIN E., WEN, QIN, BREITBACK, JUSTIN, KEMMET, CHELSY K., CLARK, KARL J., EKKER, STEPHEN C., ESSNER, JEFFREY J., MCGRAIL, MAURA
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448447/
https://ncbi.nlm.nih.gov/pubmed/22275008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23725
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados