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The Kcnq1ot1 Long Non-Coding RNA Affects Chromatin Conformation and Expression of Kcnq1, but Does Not Regulate Its Imprinting in the Developing Heart

Although many of the questions raised by the discovery of imprinting have been answered, we have not yet accounted for tissue- or stage-specific imprinting. The Kcnq1 imprinted domain exhibits complex tissue-specific expression patterns co-existing with a domain-wide cis-acting control element. Tran...

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Autori principali: Korostowski, Lisa, Sedlak, Natalie, Engel, Nora
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447949/
https://ncbi.nlm.nih.gov/pubmed/23028363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002956
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