The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria

BACKGROUND: Acquired antibodies are important in human immunity to malaria, but key targets remain largely unknown. Plasmodium falciparum reticulocyte-binding-homologue-4 (PfRh4) is important for invasion of human erythrocytes and may therefore be a target of protective immunity. METHODS: IgG and Ig...

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Auteurs principaux: Reiling, Linda, Richards, Jack S., Fowkes, Freya J. I., Wilson, Danny W., Chokejindachai, Watcharee, Barry, Alyssa E., Tham, Wai-Hong, Stubbs, Janine, Langer, Christine, Donelson, John, Michon, Pascal, Tavul, Livingstone, Crabb, Brendan S., Siba, Peter M., Cowman, Alan F., Mueller, Ivo, Beeson, James G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447948/
https://ncbi.nlm.nih.gov/pubmed/23028883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045253
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