In Vivo Inhibition of c-MYC in Myeloid Cells Impairs Tumor-Associated Macrophage Maturation and Pro-Tumoral Activities

Although tumor-associated macrophages (TAMs) are involved in tumor growth and metastasis, the mechanisms controlling their pro-tumoral activities remain largely unknown. The transcription factor c-MYC has been recently shown to regulate in vitro human macrophage polarization and be expressed in macr...

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Detalhes bibliográficos
Main Authors: Pello, Oscar M., Chèvre, Raphael, Laoui, Damya, De Juan, Alba, Lolo, Fidel, Andrés-Manzano, María Jesús, Serrano, Manuel, Van Ginderachter, Jo A., Andrés, Vicente
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447925/
https://ncbi.nlm.nih.gov/pubmed/23028984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045399
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