Interaction between IRF6 and TGFA Genes Contribute to the Risk of Nonsyndromic Cleft Lip/Palate

Previous evidence from tooth agenesis studies suggested IRF6 and TGFA interact. Since tooth agenesis is commonly found in individuals with cleft lip/palate (CL/P), we used four large cohorts to evaluate if IRF6 and TGFA interaction contributes to CL/P. Markers within and flanking IRF6 and TGFA genes...

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Autors principals: Letra, Ariadne, Fakhouri, Walid, Fonseca, Renata F., Menezes, Renato, Kempa, Inga, Prasad, Joanne L., McHenry, Toby G., Lidral, Andrew C., Moreno, Lina, Murray, Jeffrey C., Daack-Hirsch, Sandra, Marazita, Mary L., Castilla, Eduardo E., Lace, Baiba, Orioli, Ieda M., Granjeiro, Jose M., Schutte, Brian C., Vieira, Alexandre R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447924/
https://ncbi.nlm.nih.gov/pubmed/23029012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045441
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