Diabetes-Impaired Wound Healing Is Improved by Matrix Therapy With Heparan Sulfate Glycosaminoglycan Mimetic OTR4120 in Rats

Wound healing in diabetes is frequently impaired, and its treatment remains a challenge. We tested a therapeutic strategy of potentiating intrinsic tissue regeneration by restoring the wound cellular environment using a heparan sulfate glycosaminoglycan mimetic, OTR4120. The effect of OTR4120 on hea...

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Autori principali: Tong, Miao, Tuk, Bastiaan, Shang, Peng, Hekking, Ineke M., Fijneman, Esther M.G., Guijt, Marnix, Hovius, Steven E.R., van Neck, Johan W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
Soggetti:
Pharmacology and Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447910/
https://ncbi.nlm.nih.gov/pubmed/22721969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1329
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