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beta-Thalassemia in American Blacks: novel mutations in the "TATA" box and an acceptor splice site.

beta-Thalassemia genes, although often mild in their effects, are common among American Blacks. We have begun a systematic molecular analysis of beta-thalassemia mutations in this group. DNA polymorphisms in the beta-globin gene cluster were examined among 22 beta-thalassemia chromosomes. Six differ...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Antonarakis, S E, Irkin, S H, Cheng, T C, Scott, A F, Sexton, J P, Trusko, S P, Charache, S, Kazazian, H H
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1984
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6583702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.4.1154
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