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Crystal Structures of Human CaMKIα Reveal Insights into the Regulation Mechanism of CaMKI
Human calcium/calmodulin-dependent protein kinase I (CaMKI) plays pivotal roles in the nervous system. The activity of human CaMKI is regulated by a regulatory region including an autoinhibitory segment and a CaM-binding segment. We report here four structures of three CaMKIα truncates in apo form a...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447817/ https://ncbi.nlm.nih.gov/pubmed/23028635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044828 |
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