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The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment

E2F1 is responsible for the regulation of FOXM1 expression, which plays a key role in epirubicin resistance. In here, we examined the role and regulation of E2F1 in response to epirubicin in cancer cells. We first demonstrated that E2F1 plays a key role in promoting FOXM1 expression, cell survival a...

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Detalles Bibliográficos
Autores principales: de Olano, Natalia, Koo, Chuay-Yeng, Monteiro, Lara J., Pinto, Paola H., Gomes, Ana R., Aligue, Rosa, Lam, Eric W.-F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447739/
https://ncbi.nlm.nih.gov/pubmed/22802261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0559
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