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The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment
E2F1 is responsible for the regulation of FOXM1 expression, which plays a key role in epirubicin resistance. In here, we examined the role and regulation of E2F1 in response to epirubicin in cancer cells. We first demonstrated that E2F1 plays a key role in promoting FOXM1 expression, cell survival a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447739/ https://ncbi.nlm.nih.gov/pubmed/22802261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0559 |
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