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Juxtaglomerular apparatus hyperplasia under dual angiotensin blockade. A footprint of adequate RAS inhibition or a concern for renal fibrosis?

BACKGROUND: Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach. Our understanding on the molecular effects of dual...

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Autori principali: Fernandez-Fernandez, Beatriz, Ortiz, Alberto, Gomez-Guerrero, Carmen, Barat, Antonio, Martín-Cleary, Catalina, Egido, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447650/
https://ncbi.nlm.nih.gov/pubmed/22533828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-21
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