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Juxtaglomerular apparatus hyperplasia under dual angiotensin blockade. A footprint of adequate RAS inhibition or a concern for renal fibrosis?

BACKGROUND: Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach. Our understanding on the molecular effects of dual...

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Hlavní autoři: Fernandez-Fernandez, Beatriz, Ortiz, Alberto, Gomez-Guerrero, Carmen, Barat, Antonio, Martín-Cleary, Catalina, Egido, Jesús
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447650/
https://ncbi.nlm.nih.gov/pubmed/22533828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-21
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