Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

In this study the isolated compound 11-dehydrosinulariolide from soft coral Sinularia leptoclados possessed anti-proliferative, anti-migratory and apoptosis-inducing activities against A2058 melanoma cells. Anti-tumor effects of 11-dehydrosinulariolide were determined by MTT assay, cell migration as...

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Main Authors: Su, Tzu-Rong, Tsai, Feng-Jen, Lin, Jen-Jie, Huang, Han Hsiang, Chiu, Chien-Chih, Su, Jui-Hsin, Yang, Ya-Ting, Chen, Jeff Yi-Fu, Wong, Bing-Sang, Wu, Yu-Jen
Format: Artigo
Language:Inglês
Published: MDPI 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447343/
https://ncbi.nlm.nih.gov/pubmed/23015779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10081883
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